Economic Growth: Strong economic growth generally leads to higher demand for office space, benefiting DESK.US holdings and increasing its price.

Interest Rates: Rising interest rates can increase borrowing costs for REITs within DESK.US, potentially lowering their profitability and DESK.US's price.

Inflation: Higher inflation can increase operating costs for REITs within DESK.US. If rents don't keep pace, it could pressure earnings.

Occupancy Rates: Higher occupancy rates in office buildings boost rental income for REITs within DESK.US, supporting higher prices.

New Construction: Overbuilding can lead to excess supply of office space, decreasing rental rates and negatively affecting REITs within DESK.US, leading to price decreases.

REIT Performance: The performance of the underlying REITs within DESK.US directly impacts the ETF's overall value.

Investor Sentiment: Market sentiment towards real estate and REITs in general can significantly influence demand and price of DESK.US.